Human Applications Lab
John Powderly, MD, CPI
Founder and CEO
Biocytics, Inc. was founded in 2005 by John Powderly, M.D. Dr. Powderly is Triple Board Certified in Internal Medicine, Pediatrics, and Adult Medical Oncology and the only oncologist Certified Physician Investigator (CPI) in the Charlotte region. Dr. Powderly graduated from Georgetown Medical School as a Lawrence Dean Scholar and performed his Residency in Combined Medicine and Pediatrics Medicine at the University of Texas Health Science Center. Additionally, Dr. Powderly was an Oncology Fellow at the University of North Carolina at Chapel Hill where he held triple faculty staff appointments in the Departments of Medicine, Pediatrics, and Emergency Medicine. While at UNC-Chapel Hill, Dr. Powderly performed cancer research focusing on melanoma and tumor immunology. Moreover, while in medical school, Dr. Powderly performed immunotherapy research under the direction of Dr. Steven Rosenberg at the National Cancer Institute. Dr. Powderly has served as the Principal Investigator on numerous clinical trials and currently serves on the speakers bureau for several large pharmaceutical and biotechnology companies where he presents talks on tumor immunotherapy.
Midan Ai, PhD
Midan recieved her Bachelor of Science in Biology from Lanzhou University, Lanzhou, China. She went on to get her Master of Science in Cancer Biology from Xiangya School of Medicine, Central South University, Changsha, China. From there she got her PhD in Cancer Biology from the University of Texas, Department of Experimental Therapeutics, M.D. Anderson Cancer Center, Houston, Texas. She was a Postdoctor Fellow in the Department of Immunology at M.D. Anderson Cancer Center where she was involved in the Pre-clinical study on in vivo animal models to test the therapeutic effects of hypoxia specific chemotherapy evofosfamide combined with immunotherapy aCTLA-4 and aPD-1 for prostate cancer. Form the excellent therapeutic effects as shown in her study, combination of checkpoint blockade antibody aCTLA-4 and aPD-1 with evofosfamide will move to clinical trial in the near future. She is an expert in in vitro lymphocyte analysis based on multi-color flow cytometry, Luminex, ELISA, Elispot and immunofluorescence to explore the pharmacological mechanism of the drug combination.
Katie Gradert, BS
Human Applications Lab Supervisor
Katie received her Bachelor of Science in Biomedical Engineering from The Ohio State University, Columbus, Ohio. She graduated magna cum laude. In her undergraduate career she worked at Polymer Group, Inc in Research and Development to design and lead an experimental trial to determine the optimal processing conditions on Reifenhauser Reicofil Meltblown line. Upon graduation she came to Carolina BioOncology Institute and worked as a Clinical Research Coordinator for Phase 1 oncology immunotherapy clinical trials involving Stage IV cancer patients. Now she is working in the technical supervision of Biomedical Engineering for the Human Applications Lab. Responsibilities include ordering and maintaining inventory of reagents and products, and maintenance and regulation of biomedical equipment. Correspondence and management of accounts. Duties also include development of Standard Operating Procedures with adherence to FDA standards of GMP, GCP, GLP and GTP.
Amy Austin, MLT
Amy works at Carolina BioOncology Institute as our Operations Manager and one of our Clinical Research Coordinators. She has over 4 years of experience in the clinical laboratory and over 10 years of managerial experience in various fields. She is a certified Medical Laboratory Technician and while attending CPCC she was awarded The Outstanding Student in Medical Laboratory Technology for her graduating class. She uses her managerial skills and knowledge of lab procedures to ensure the laboratory runs safely and efficiently. She is in charge of security and IT. She is also currently coordinating a Phase I Immunotherapy Clinical Trials.